Nobel Prize in chemistry awarded to Kagan and Soai for research solving 'mirror image' mystery

STOCKHOLM — Henri B. Kagan and Kenso Soai won the Nobel Prize in chemistry Wednesday for their efforts to resolve mysterious mirror images in chemical molecules, a discovery that transformed modern medicine. Many molecules of life come in versions that look alike but aren’t exactly identical, like right and left hands. One mirror image of the chemical carvone smells like mint, for example, while the other has a whiff of caraway. When designing drugs to treat diseases, scientists want to be choosy about which mirror image they’re getting. They want the version of a molecule that’ll treat a cold, not the kind that’ll make the sniffles worse. Kagan and Soai found ways to make chemistry pick a side, designing and manipulating reactions to produce the desired mirror image. “This is probably the coolest experiment in organic chemistry,” said Peter Somfai, a member of the Nobel Committee for Chemistry. “Taken together, the groundbreaking discoveries by Henri Kagan and Kenso Soai have reshaped our understanding of molecular chirality — how it is created, amplified and transmitt